Proteome Screening, Identification and Designing of Potent Antigenic Peptides of Neisseria Meningitides: A Cause of Meningitis

Abstract Meningitis is an acute inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges. Meningitis can be life-threatening because of the inflammation’s proximity to the brain and spinal cord; therefore, the condition is classified as a medical emergency. The scope of the current work is to predict and […]

Insilico Annotation and Prediction of Mutational Hotspots of Optineurin (OPTN), a Novel Approach for Structural Analysis and Peptide Designing

Abstract One of the major causes of blindness is primary open-angle glaucoma, which affects millions of elderly people worldwide. Optineurin (OPTN) has recently been linked to glaucoma, a major cause. Mutations in OPTN have been reported in patients, particularly those with normal pressure glaucoma. The purpose of analysis was to determine the potential regions of […]

Production and Qualitative Analysis of Secondary Metabolites of Staphylococcus Bacteria having Antibiotic Activity

Abstract Antibiotics are one of the most important commercially exploited secondary metabolites produced by the bacteria and employed in a wide range. Most of the antibiotic producers used today are the soil microbes and the antibiotics are the secondary metabolites of these cells. With the increasing applications of these commercially available antibiotics they are becoming […]

Analysis of Inhibitory Activity of Ricin Extracted from Ricinus Communis on Human Cancer Cell Lines and testing its activity on HIV receptor CD4 using Insilico analysis

Abstract Castor (Ricinus communis L.) is one of the oldest cultivated oil crops in the world. The unique oil produced in castor seeds contains ricinoleic acid, an essential product that is widely used as a raw material in numerous commercial applications. Ricin one of the storage protein of the seed is an cytotoxin used in […]

Isolation and Extraction of Elastase Producing Bacteria from Natural Habitat (Water-Soil Sample) and targeting it to APP, A Cause of Alzheimer’s disease

Abstract Alzheimer’s disease (AD) is the most common form of dementia. There is no known cure for the disease, in fact it worsens as it progresses, and eventually leads to death. In this work the main focus was tro extract the protein elastase and intern use it to target the APP protein, a cause of […]