Abstract EPX gene is a member of the peroxidase gene family and is expressed in eosinophils. The gene is found in a cluster of three peroxidase genes at chromosome 17q23.Mutations in this gene result in eosinophil peroxidase deficiency. Till date, there is very less work undertaken on the gene. Thus the current work aims to […]
Abstract The objective of the work is to analyze the diabetic protein Leptin, a major cause of several syndromes in the current era. The work involves the characterization of the Leptin protein and to establish its relation in Obesity. The protein is targeted for the treatement of obesity symptoms using several chemical ligands. The work […]
Abstract Epilepsy is one of the genetic diseases that is existing from the past. Though it is less observed statistically, it has a very bad effect on the victim. There are several approaches to resolve certain symptoms of the disease. Drug targeting is one of the routinely used approaches for the same. The current work […]
Abstract The major flavour precursors in the genus Allium include alliin, isoalliin, proliin and methiin, members of the alkyl Cysteine Sulfoxide group (CSOs). The path of synthesis of alkyl Cysteine Sulphoxides, or flavour precursors, in the Alliums are still speculative. There are two proposed routes for alliin biosynthesis, one is from serine and allyl thiol […]
Abstract Meningitis is an acute inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges. Meningitis can be life-threatening because of the inflammation’s proximity to the brain and spinal cord; therefore, the condition is classified as a medical emergency. The scope of the current work is to predict and […]
Abstract One of the major causes of blindness is primary open-angle glaucoma, which affects millions of elderly people worldwide. Optineurin (OPTN) has recently been linked to glaucoma, a major cause. Mutations in OPTN have been reported in patients, particularly those with normal pressure glaucoma. The purpose of analysis was to determine the potential regions of […]
Abstract Antibiotics are one of the most important commercially exploited secondary metabolites produced by the bacteria and employed in a wide range. Most of the antibiotic producers used today are the soil microbes and the antibiotics are the secondary metabolites of these cells. With the increasing applications of these commercially available antibiotics they are becoming […]
Abstract Castor (Ricinus communis L.) is one of the oldest cultivated oil crops in the world. The unique oil produced in castor seeds contains ricinoleic acid, an essential product that is widely used as a raw material in numerous commercial applications. Ricin one of the storage protein of the seed is an cytotoxin used in […]
Abstract Alzheimer’s disease (AD) is the most common form of dementia. There is no known cure for the disease, in fact it worsens as it progresses, and eventually leads to death. In this work the main focus was tro extract the protein elastase and intern use it to target the APP protein, a cause of […]
Abstract Some of the fruits and vegetables that are used in our daily life have proved to be effective in treating the microbial and fungal infections. The current work was done to identify the anti microbial capacity of selected fruit extracts so as to design a more simple and economic means to treat these infections. […]