Analysis of RAS Subfamily involved in Cancer via in silico Approach and Designing of Potent Drug against Cancer

Abstract RAS subfamily belongs to a class of proteins called small GTPase, which are a group of hydrolase enzymes that can bind (‘on state’) and hydrolyze (‘off state’) guanosine triphosphate (GTP). Hence, RAS proteins act as binary molecular switches and play a consequential role in intracellular signal transduction which regulates processes such as actin cytoskeletal […]

Analysis and targeting of NRG1 protein via in-silico Drug Design approach (Structure based) for the treatment of Schizophrenia

Abstract Neuregulin-1 (NRG-1) is a gene that helps regulate synaptic plasticity and mutations in NRG-1 have been found in patients with schizophrenia. Researchers have found that the prefrontal cortex expresses much higher levels of NRG-1 in humans with schizophrenia. Researchers have found that the mice grown with over expression of NRG-1 had schizophrenia like symptoms […]

Pharmacogenomics in Diabetes Mellitus: Pathway to Personalized Medicine

Abstract Diabetes, growing global health burden is a Multifactorial, heterogeneous group of disorders characterized by deficiency or failure in maintaining normal glucose homeostasis. The prevalence of Diabetes is rising across the globe at an alarming rate with India and china facing the greatest challenges with worsening trend affecting younger age groups. Diabetes and its complications […]

Enhanced Growth in the Clonal Propagated Plants

Abstract Micro propagation has the potential to provide very high multiplication rates of selected true genotypes. It allows rapid production of high quality, disease free and uniform planting materials irrespective of weather or season. The paper highlights studies on the same, outlines potential of using single to multiple co-cultures combinations of microbe that were in […]

Qcciniaherb®: A Novel Herbal Medicine for Diabetes

Abstract Diabetes is prevalent world-wide and is stated to be a silent killer. Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. There are hundreds of medicinal plants that have a long history of curative properties against various diseases and ailments. A variety of […]