Proteome Screening, Identification and Designing of Potent Antigenic Peptides of Neisseria Meningitides: A Cause of Meningitis

Abstract Meningitis is an acute inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges. Meningitis can be life-threatening because of the inflammation’s proximity to the brain and spinal cord; therefore, the condition is classified as a medical emergency. The scope of the current work is to predict and […]

Insilico Annotation and Prediction of Mutational Hotspots of Optineurin (OPTN), a Novel Approach for Structural Analysis and Peptide Designing

Abstract One of the major causes of blindness is primary open-angle glaucoma, which affects millions of elderly people worldwide. Optineurin (OPTN) has recently been linked to glaucoma, a major cause. Mutations in OPTN have been reported in patients, particularly those with normal pressure glaucoma. The purpose of analysis was to determine the potential regions of […]