Abstract This is a prospective study conducted in the SRM Medical College Hospital and Research Centre, Tamil Nadu from April 2010 to July 2010 to find out the prevalence of NFGNB in the clinical specimens and to isolate and identify the prevalent NFGNB from different clinical samples received in SRM medical college laboratory. Confirmation of […]
Abstract Osteoarthritis (OA) is a degenerative joint disease which occurs mainly due to aging and mechanical stress. So far only temporary methods like giving pain alleviating drugs are employed for the treatment of OA but a permanent solution to cure the disease has not yet been established. The need of the hour is to find […]
Abstract The increased incident and rapid spread of drug resistance in Plasmodium falciparum has become a major public health obstacle in India. Multi-Drug Resistance1 (MDR1) Protein has been one of the major protein to resist various types of antimalarial drugs. There is a need to develop new drugs against malaria combating the drug resistance ability […]
Abstract “Listeriosis” is the recent pandemic caused by a bacterium named Listeria monocytogenes an intracellular pathogen causes very high mortality rates in the United States. In the Current study, an effort was taken to design a Potent Subunit vaccine against L. monocytogenes applying the reverse vaccinology approach. The method includes screening of complete proteome based […]
Abstract Single-nucleotide polymorphisms (SNPs) play a major role in the understanding of the genetic basis of many complex human diseases. The current study reports, of the total of 682 SNPs in the CHK2 gene, 10 non-synonymous SNPs (nsSNPs) were identified as functionally significant. SIFT, PolyPhen and I -Mutant programs were used to analyze the nsSNPs. […]
Abstract Rennet, a microbial coagulant, is obtained from Mucor miehei which is isolated from ruminant stomach. Cheese is one of the milk product which is produced from the enzyme rennet. The aim of the current work was to produce cheese from Rhizomucor miehei which is a common inhabitant of cow dung. Pure culture of the […]
Abstract Globular protein Bovine Serum Albumin is water soluble and is sensitive to Low Power mm Wave (Micro wave) irradiation leading to Coagulation at the isoelectric Point.The objective of the work was to study the effect of these radiations on the coagulation and light absorbance of purified bovine serum albumin protein. When a heat stress […]
Abstract Date rape drug refers to a drug that can be used to assist in the execution of a sexual assault, such as date rape. Sexual assault is any type of sexual activity that a person does not agree to. Drugs used to facilitate rape may have sedative, hypnotic, dissociative and/or amnesiac effects, and can […]
Abstract Butyryl cholinesterase (BCHE) is a protein belonging to ester lipase super family. It hydrolyzes choline esters in addition to its role in nerve impulse transmission. BCHE has three active sites located at 226, 353 and 456 which are responsible for acyl ester intermediate, and charge relay system. Among the three sites, 226 (serine) have […]