Molecular Characterisation of HBB and associated Polymorphism rs33915217 Involved in Beta Thalassemia

Abstract Mutations in the HBB (Haemoglobin subunit beta) can cause several diseases. β-Thalassemia is one such disease which has no cure. β-Thalassemia can cause abnormal Beta chains in the haemoglobin molecule or in some cases be absent altogether.  Numerous polymorphisms have been identified which can cause β-Thalassemia but one of the more prominent ones is […]

Prediction of Protein Secondary Structure Using LIBSVM and SSVM with different Kernel Function

Abstract Bioinformatics and computational biology is the emerging field of research in current era. Proteomics is solitary of the prime areas of research in bioinformatics. The general function of proteins is mostly dictated by structure. Prediction of secondary structure plays a key role in its further prediction of tertiary structure. Several techniques have been proposed […]

Isolation and Identification of Pseudomonas aeruginosa from different sources (soil, wound, urine) and Checking its MIC with various Antibiotics

Abstract Pseudomonas is a group of bacteria found in soil, water, skin flora and most man- made environments throughout the world. Pseudomonas infections may cause disease, generalized inflammation and sepsis. The targeted organism for this organism are the lungs, the urinary tract, and kidneys, the result can be fatal. It can also be found on medical […]

Targeting Human Bocavirus VP-2 Protein by Combining Pharmacophore, Molecular Docking and ADME-Tox Approaches to Identify Best-Optimized Novel Drug Candidate

Abstract Human bocavirus (HBoV) belongs to a parvoviridae family. It has a single-stranded DNA etiologic agent and is known to cause lower respiratory tract infections in small and young children all over the world. Currently, there is no treatment or vaccination. The aim of the study was to describe the Human bocavirus VP 2 protein […]