Prevalence and Relative Evaluation of Adverse Drug Reactions in Tuberculosis Patients undergoing DOTS in Karad region

Abstract Tuberculosis (TB), a multisystemic disease with myriad presentations and manifestations, is the most common cause of infectious disease–related mortality worldwide. To find out adverse drug reactions induced due to Directly Observed Treatment, Short-course (DOTS), a study was undertaken to assess the prevalence rate and pattern of adverse drug reactions (ADR) in DOTS with focus […]

Molecular Modeling and Insilico Structural analysis of Mycobacterium Tuberculosis Mycosin 1

Abstract The Mycosins are subtilin like serine proteases present in Mycobacterium Tuberculosis. They have been reported to play a prominent role in Lysin degradation and Biotin metabolism. MycP-1 protein is one of the major proteins expressed in the patients infected with Mycobacterium Tuberculosis. The key metabolic process involved in Bacilli growth and survival is Biotin […]

PFMDR1- A Potential Target to combat the Mutli Drug Resistance in Malaria

Abstract Plasmodium Falciparum Malaria (PFM) infection is a leading source of life killing diseases such as Cerebral Malaria, Nephritis, Hepatic disorder and Severe Anaemia. In the current study, we use computational methods in order to improve our understanding of the complex disease interactions of Plasmodium Falciparum Malaria. Through our work we tried to emphasize the […]


Abstract Diabetes is a chronic metabolic disorder in which the body cannot regulate the amount of sugar (specifically, glucose) in the blood. India, already the diabetic capital of the world, 70 million people might get affected by 2015. Prediabetes is a condition in which blood glucose levels or A1C levels are slightly higher than normal. […]

Optimization for acid pre-treatment of Sweet Sorghum Bagasse to obtain fermentable sugars using Response Surface Methodology

Abstract Sweet Sorghum Bagasse (SSB), one of the most abundant lignocellulostic residues represents an attractive renewable resource for bioconversion of energy. The present study was focused on utilization of SSB to obtain higher yield of fermentable sugars so as to take it as a substrate in ethanol production. As lignin is found to hinder the […]

A Biological Approach to Harden the Micropropagated Plants using the Soil Microorganisms- Micro and Macro Nutrient Analysis

Abstract Micropropagation is the technique for rapid multiplication of the selected plants within a short time period. The plants which have been raised in-vitro are delicate and cannot withstand the adverse conditions outside the laboratory [1]. Such plants not only face stress above the soil, but also within the soil i.e. in its roots. The […]

Role of Genetic Transformation in Recombinant DNA Technology and Demonstration Using Escherichia coli strain DH5alpha

Abstract In Molecular Biology, genetic transformation occurs when an organism’s character is changed or modified by inserting one or more desired gene(s) in order to utilize them for different purposes, for instance, the betterment of plant species by insertion of genes coding for drought, pest, and frost resistance, transformation of common bacterium E. coli in […]

Study on the Prevalence of Virulent genes in Escherichia coli isolated from Fish using multiplex PCR

Abstract A one shot multiplex Polymerase Chain Reaction PCR was developed for detecting 6 virulent genes of diarrheagenic E.coli from fish and shrimps. In order to differentiate between 5 categories of diarrheagenic E.coli ,I selected the target genes eae for Enteropathogenic E.coli(EPEC), ipaH for Enteroinvasive E.coli (EIEC) ,stx for Enterohaemorragic E.coli (EHEC), aggR for Enteroaggregative […]