Computational characterization and structural modulation of Glycerol-3-Phosphate Acyl Transferase relevant to medicinal significance

Abstract Glycerol 3 phosphate acyltransferase (GPAT, EC: is recognized as a key player of cellular acyltransferase metabolism. It catalyzes the chain initiation step leading to triglyceride biosynthesis. The protein sequence of GPAT was retrieved from GenBank. However, a substantial and well defined structure is not available for this sequence. The 3D structure of GPAT […]

Insilco Characterization and Predication of Mutation Host Pots I ACTA1 and Designing the Mutable Vector for Carrying the Peptide

Abstract Nemaline myopathy is a disease that primarily affects skeletal muscles due to mutations in the Actin Protein family. The purpose of analysis was to determine the potential regions on the ACTA1 protein that have maximum probability of mutations. The identification of the disordered regions was performed using various tools like DISEMBL, GLOB PLOT and […]

Synergistic and inhibitory effects of Plant Growth regulators on Soybean (Glycine max l. Merrill)

Abstract As the title indicates the current work aims to identify the inhibitory effect of plant growth regulators on the growth conditions of soybean. The work revealed that, seed yield and yield components were significantly increased by NAA at 20 ppm over other treatments and control. The application of brassinosteroid at 25 ppm, mepiquat chloride […]

Isolation and Identification of Fungi from Spoiled food samples and testing their Antibiotic efficacy

Abstract Spoilage is the process in which food deteriorates to the point where in it is not edible to humans. Micro-organisms are mainly responsible for food spoilage which includes bacteria and fungi. A study was carried out on the fruits that were spoiled due to the fungal infection. Rhizopus, Trichoderma, Penicillium and Aspergillus were isolated […]

Prospects for Drug Designing: Similar Conserved Interactions of Bim with MCL-1 AND BCL-2

Abstract Structures of antiapoptotic Bcl-2-family proteins that protect the cells against death like Mcl-1 and Bcl-2 bear a surface groove into which the α-helical BH3 regions of certain pro-apoptotic proteins bind. This is done by occupying the hydrophobic pocket formed by the close proximity of their BH1-3 domains. The interactions among these proteins determine whether […]

Character Association and Path Analysis in Rice (Oryza sativa L.) Genotypes for cold tolerance

Abstract Genotypic and phenotypic correlation among sixteen component characters was studied in 52 genotypes of Rice. Association analysis of parents revealed that Days to 50% flowering, plant height, seedling maturity after transplanting, number of productive tillers, Panicle excertion had high significant positive correlation with cold tolerance. Number of seeds/head, 100 seed weight, head diameter and […]