Studies on Cellulase Production by Solid state Fermentation using Sweet Sorghum bagasse

Abstract The present study involves production of cellulolytic enzymes by a newly isolated strain of Aspergillus niger isolated from decaying sugarcane bagasse. Solid-state-fermentation was employed using sweet sorghum bagasse as the substrate for the production of enzyme. One factor at a time approach was used to optimize the process variables like moisture content, pH, temperature, […]

Extraction, Purification and Analysis of Anti cancer activity of Ricin on Colon Cancer Cell Lines and Testing its Efficacy using Insilco Docking

Abstract Ricin, one of the well known plant toxins has played a vital role in the history of medicine. It is usually extracted from Ricinus Communis, a common plant. The use of these proteins in medical treatment since ancient times is reviewed. Later the proteins played important roles in the early days of immunological research […]

Influence of Parameters and Differences in Results of Microsatellite Detection Software: A Bioinformatics Study

Abstract Microsatellites are small nucleotide repeats which are formed by tandem repetition of motifs of size 1-6 bp. These repeats play an important role in Genome evolution, Associated with various diseases, Used as molecular markers in DNA Fingerprinting, Population Genetics, Paternity Studies, Forensics, etc. Various bioinformatics tools are being used for extraction of STRs during […]

A Novel Analysis of Diabetes Mellitus by Using Expert System Based on Brain Derived Neurotrophic Factor (BDNF) Levels

Abstract In this paper a novel concept of designing and building intelligent expert system for the detection and diagnosis of Diabetes Mellitus is introduced. The expert system classification is based on critical diabetic parameters like Brain-Derived Neurotrophic Factor (BDNF) levels, and Fasting Blood Glucose (FBG). The proposed rule-based expert system constructs large-scale knowledge-base based on […]

Production of alpha Amylase from Soil Bacteria and characterization of the enzyme activity and Kinetic Study

Abstract Enzymes obtained from micro organism are more stable and economic. Among the commercially valuable microbial enzymes, Amylases are most important and are of great significance in present day industry. Amylases are used for various purposes such as in Brewing industry, Food additive, also used in Clothing and Dishwasher Detergents to dissolve starches. In the […]

Docking studies of Alzheimer Cathepsin B protein-ligand complex in presence and absence of water molecules: Insight to enhance docking accuracy of AutoDock4.0

Abstract Alzheimer’s disease (AD) or Senile Dementia of the Alzheimer Type (SDAT) is a progressive neurologic brain disease leading to irreversible loss of neurons and loss of intellectual abilities, including memory and reasoning, which impedes social or occupational functioning. During the course of the disease, plaques and tangles develop within the brain. This causes neuronal […]

Amplification of 16sr RNA for Staphylococcus Aureus Isolates From Food Samples

Abstract Staphylococcus aureus, a gram positive bacterium, is one of the most common clinical and food borne pathogens worldwide. S .aureus produces very important virulence factors including Staphylococcus enterotoxins (SEs) which are the main causes of diarrhea, vomiting and other symptoms associated with S.aureus infections. The conventional methods used for identification of S.aureus are time […]

Prevalence and Comparative Assessment of adverse Drug Reactions in Dots with Focus on HIV Negative patients in Karad Region

Abstract TB is major public health problem in Asia especially in India. In India, annually more than 3,30,000 patients die due to tuberculosis (TB). Recently due to multiple drug therapy, cases of adverse drug reactions are increasing. Nowadays TB and Human immunodeficiency virus (HIV) are most common, and having high prevalence rate. Treatments to both […]

Biochemical Behavior of Some Newly Synthesized Poly Nuclear Complexes of Tungsten

Abstract Tungsten is of interest due to the role in Biological stystem. DithioCarbamates, the derivative of Dithiocarbamates acids are important on account of their wide applications; it contains Sulphur donor atoms which have tendency to from complexes with Tungsten Metal. Polynuclear complexes of Tungsten have been Synthesized and characterized by different methods. Physical and Analytical […]

Identification of Phytase producing Bacteria C43 isolated from cattle shed soil samples of Hyderabad, A.P

Abstract Phytases are the enzymes which hydrolyze phytic acid, a major storage form of phosphorus in cereals and legumes, to less phosphorylated myo-inositol derivatives releasing inorganic phosphate. The supplementation of animal feed with phytases reduces the cost of diets by removing or reducing the need for supplemental inorganic phosphate and increases the bioavailability of phosphorous […]