Abstract Tuberculosis (TB), a multisystemic disease with myriad presentations and manifestations, is the most common cause of infectious disease–related mortality worldwide. To find out adverse drug reactions induced due to Directly Observed Treatment, Short-course (DOTS), a study was undertaken to assess the prevalence rate and pattern of adverse drug reactions (ADR) in DOTS with focus […]
Abstract The Mycosins are subtilin like serine proteases present in Mycobacterium Tuberculosis. They have been reported to play a prominent role in Lysin degradation and Biotin metabolism. MycP-1 protein is one of the major proteins expressed in the patients infected with Mycobacterium Tuberculosis. The key metabolic process involved in Bacilli growth and survival is Biotin […]
Abstract Plasmodium Falciparum Malaria (PFM) infection is a leading source of life killing diseases such as Cerebral Malaria, Nephritis, Hepatic disorder and Severe Anaemia. In the current study, we use computational methods in order to improve our understanding of the complex disease interactions of Plasmodium Falciparum Malaria. Through our work we tried to emphasize the […]
Abstract Diabetes is a chronic metabolic disorder in which the body cannot regulate the amount of sugar (specifically, glucose) in the blood. India, already the diabetic capital of the world, 70 million people might get affected by 2015. Prediabetes is a condition in which blood glucose levels or A1C levels are slightly higher than normal. […]
Abstract Sweet Sorghum Bagasse (SSB), one of the most abundant lignocellulostic residues represents an attractive renewable resource for bioconversion of energy. The present study was focused on utilization of SSB to obtain higher yield of fermentable sugars so as to take it as a substrate in ethanol production. As lignin is found to hinder the […]
Abstract Micropropagation is the technique for rapid multiplication of the selected plants within a short time period. The plants which have been raised in-vitro are delicate and cannot withstand the adverse conditions outside the laboratory [1]. Such plants not only face stress above the soil, but also within the soil i.e. in its roots. The […]
Abstract In Molecular Biology, genetic transformation occurs when an organism’s character is changed or modified by inserting one or more desired gene(s) in order to utilize them for different purposes, for instance, the betterment of plant species by insertion of genes coding for drought, pest, and frost resistance, transformation of common bacterium E. coli in […]
Study on the Prevalence of Virulent genes in Escherichia coli isolated from Fish using multiplex PCR
Abstract A one shot multiplex Polymerase Chain Reaction PCR was developed for detecting 6 virulent genes of diarrheagenic E.coli from fish and shrimps. In order to differentiate between 5 categories of diarrheagenic E.coli ,I selected the target genes eae for Enteropathogenic E.coli(EPEC), ipaH for Enteroinvasive E.coli (EIEC) ,stx for Enterohaemorragic E.coli (EHEC), aggR for Enteroaggregative […]
Abstract Phosphoproteins are found to be enriched in intrinsic sequence disorder (ID), and this enrichment is related with both cellular location and phosphorylation status. The majority of phosphorylation sites are located outside the structural protein motifs but were mostly located in regions of ID. ID proteins are also very important in certain epigenetic and evolutionary […]
Abstract Iron is an extremely important element whose function is involved in the oxygen transport and it participates in the electron transfer reactions and various redox potential reactions. Ferritin, the globular cytoplasmic protein is highly conserved and is involved in the regulation of the flow of iron into and out of the cell. Ferritins play […]