Efficacy of some natural flavanoids against PDK-1 Kinase: An insilico Molecular docking and Molecular Dynamic Simulation study

Abstract PDK-1, 63Da serine thionine kinase has a well-known role in cell growth regulation and differentiation. It is over expressed in many cancer cells and considered as a novel target of many anti-cancer drugs. In the present study we have explored the affinity and interaction of some plant derived natural flavanoids against PDK-1 with insilico […]