Studies on Cellulase Production by Solid state Fermentation using Sweet Sorghum bagasse

Abstract The present study involves production of cellulolytic enzymes by a newly isolated strain of Aspergillus niger isolated from decaying sugarcane bagasse. Solid-state-fermentation was employed using sweet sorghum bagasse as the substrate for the production of enzyme. One factor at a time approach was used to optimize the process variables like moisture content, pH, temperature, […]

Influence of Parameters and Differences in Results of Microsatellite Detection Software: A Bioinformatics Study

Abstract Microsatellites are small nucleotide repeats which are formed by tandem repetition of motifs of size 1-6 bp. These repeats play an important role in Genome evolution, Associated with various diseases, Used as molecular markers in DNA Fingerprinting, Population Genetics, Paternity Studies, Forensics, etc. Various bioinformatics tools are being used for extraction of STRs during […]

A Novel Analysis of Diabetes Mellitus by Using Expert System Based on Brain Derived Neurotrophic Factor (BDNF) Levels

Abstract In this paper a novel concept of designing and building intelligent expert system for the detection and diagnosis of Diabetes Mellitus is introduced. The expert system classification is based on critical diabetic parameters like Brain-Derived Neurotrophic Factor (BDNF) levels, and Fasting Blood Glucose (FBG). The proposed rule-based expert system constructs large-scale knowledge-base based on […]

Docking studies of Alzheimer Cathepsin B protein-ligand complex in presence and absence of water molecules: Insight to enhance docking accuracy of AutoDock4.0

Abstract Alzheimer’s disease (AD) or Senile Dementia of the Alzheimer Type (SDAT) is a progressive neurologic brain disease leading to irreversible loss of neurons and loss of intellectual abilities, including memory and reasoning, which impedes social or occupational functioning. During the course of the disease, plaques and tangles develop within the brain. This causes neuronal […]

Prevalence and Comparative Assessment of adverse Drug Reactions in Dots with Focus on HIV Negative patients in Karad Region

Abstract TB is major public health problem in Asia especially in India. In India, annually more than 3,30,000 patients die due to tuberculosis (TB). Recently due to multiple drug therapy, cases of adverse drug reactions are increasing. Nowadays TB and Human immunodeficiency virus (HIV) are most common, and having high prevalence rate. Treatments to both […]

Identification of Phytase producing Bacteria C43 isolated from cattle shed soil samples of Hyderabad, A.P

Abstract Phytases are the enzymes which hydrolyze phytic acid, a major storage form of phosphorus in cereals and legumes, to less phosphorylated myo-inositol derivatives releasing inorganic phosphate. The supplementation of animal feed with phytases reduces the cost of diets by removing or reducing the need for supplemental inorganic phosphate and increases the bioavailability of phosphorous […]

Molecular Mapping of High Iron and Zinc Rich Regions in Rice (Oryza sativa L.) Grains Using Microsatellite Markers

Abstract Rice (Oryza sativa L.) is a primary source of food for billions of people throughout the world, yet it contains insufficient levels of the key micronutrients iron, zinc and vitamin A to meet the daily dietary requirements. Biofortification of staple food crops has thus been considered a sustainable strategy to overcome the problem of […]

Analysis of RAS Subfamily involved in Cancer via in silico Approach and Designing of Potent Drug against Cancer

Abstract RAS subfamily belongs to a class of proteins called small GTPase, which are a group of hydrolase enzymes that can bind (‘on state’) and hydrolyze (‘off state’) guanosine triphosphate (GTP). Hence, RAS proteins act as binary molecular switches and play a consequential role in intracellular signal transduction which regulates processes such as actin cytoskeletal […]