Phyto-Chemical Analysis And Anti-Microbial Activity Of Murraya koenigii

Author Name(s): Dr. Nirmala Babu Rao, O. Sita Kumari, *Rajesh Goud Gajula
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Murraya koenigii belongs to the family Rutaceae, commonly known as Curry leaf plant is a highly valued plant for its medicinal value and characteristic aroma. The plant consists of a rich source of carbazole alkaloids. The chloroform, petroleum ether, ethanol and ethyl acetate extracts of roots of the plant were screened for photochemical properties and antimicrobial activity for Staphylococcus aureus, Salmonella typhi, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Candida albicans and Aspergillus niger.


Murraya koenigii, Photochemical screening, Antimicrobial activity, Leaves, Roots.


Murraya koenigii (Linn,) commonly known as Curry leaves is spread throughout India up to an altitude of 1500 metres. The leaves of the plant are used as flavoring agent (Manisha Vats et al.) Medicinally, these leaves are used in dysentery, diarrhea and to prevent vomiting. The fruits and leaves are used as a source of an essential oil which finds use as a fixative for heavy type of soap perfume. Leaves, root and bark are used as tonic, stomachic and carminative. Juice made of roots is used in medicines as it provides relief from renal pain (Kirtikar K.R et al.). The leaves are imparipinnate with obliquely ovate or rhomboid shape. Phytochemically these leaves found to contain alkaloid (Atta-Ur-Rahman et al. and Reisch et al.) and volatile oil (Wong, KC et al.) Leaves are said to possess anti-inflammatory, anti feedant activity (Srivastava et al.) The medicinal value of the leaf has been reported as antibacterial (Thomas, E et al.). The most important chemical constitutents responsible for its intense characteristic aroma are P-gurjunene, P-caryophyllene, P-elemene and O-phellandrene (Vandana Jain et al.). Bark and roots are used as stimulant and externally to treat eruptions and bites of poisonous animals. Green leaves are eaten raw for cure of dysentery, and for checking vomiting, diarrhoea. Leaves and roots are also used traditionally asanalgesic, bitter, anthelmintic, curing piles, inflammation, itching and are useful in blood disorders and leucoderma (Nadkarni KM et al. and Kirtikar KR et al.). Several systematic scientific studies are also being conducted regarding the efficacy of whole plant and its parts in different extract forms for the treatment of several diseases.


In the present work, the comprehensive Photochemical contents of M. koenigii the extracts from leaves and roots with their related antimicrobial activities were demonstrated for the first time. Our investigation results showed evidence that all the tested compounds are capable of providing a zone of inhibition for Staphylococcus aureus is high with 1.2cm at 2.5μg/ml concentration and for Candida parapsilosis the zone of inhibition is 0.9cm with leaf extract and providing a zone of inhibition for Staphylococcus aureus is 1.0cm at 2.5 μg/ml concentration and 0.6cm for Candida parapsilosis when tested with root extracts.

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